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    Loss of Dicer fowls up centromeres

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    loss_of_dicer.pdf (151.9Kb)
    Date
    2004-08
    Author
    White, Sharon A
    Allshire, Robin C
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    Abstract
    Centromeres, specialized regions on chromosomes, are essential for accurate chromosome segregation during cell division. In fission yeast, the RNA interference machinery has a pivotal function in the assembly of centromeric heterochromatin, which mediates sister centromere cohesion. Studies in vertebrate cells now suggest that many aspects of this process are conserved.
    URI
    doi:10.1038/ncb0804-696
    http://www.nature.com/nature
    http://hdl.handle.net/1842/716
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