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Please use this identifier to cite or link to this item: http://hdl.handle.net/1842/690

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Title: A viable herd of genetically uniform cattle - Deleterious alleles seem to have been purged in a feral strain of inbred cows
Authors: Visscher, P M
Smith, D
Hall, SJG
Williams, JL
Issue Date: 18-Jan-2001
Citation: Visscher PM, Smith D, Hall SJG, Williams JA, NATURE, 409 (6818): 303-303 JAN 18 2001
Publisher: Nature Publishing Group
Abstract: Inbreeding, which can lead to the loss of genetic variation or the accumulation of deleterious alleles, has been shown to reduce fitness in wild (1), zoo, laboratory (2) and farmed (3) animals. But it has been proposed that when combined with selection, inbreeding may purge deleterious alleles (4). Here we provide support for this hypothesis in a study of the Chillingham cattle, which shows that this viable herd is almost genetically uniform. The homozygosity of this herd far exceeds that of other cattle (5) and that found in wild populations of other mammalian species (6,7).
Keywords: herd
genetically
uniform
cattle
Deleterious
alleles
feral strain
inbred
cows
URI: http://hdl.handle.net/1842/690
Appears in Collections:Biological Sciences publications

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