The School of Chemistry at the University of Edinburgh is the top rated for teaching and research in Scotland.

Presented here is a selection of research from the School

Recent Submissions

  • Luminescence-based optical sensors towards in vivo analysis 

    Mohamad, Mohd Fuad Bin (The University of Edinburgh, 2018-07-09)
    Continuous monitoring of physiological parameters such as pH and oxygen (O2) are of great importance in determining the health status of a patient. Arterial blood gas analysis is a current clinical method used to measure ...
  • High pressure synthesis and neutron diffraction studies of new magnetic manganites 

    McNally, Graham Michael (The University of Edinburgh, 2018-07-09)
    With the discovery of appreciable room temperature magnetoresistance (MR) in high Curie temperature (Tc) ferrimagnetic double perovskites such as Sr2FeMoO6, research surrounding other materials of this type has expanded. ...
  • Bimetallic actinide complexes for small molecule activation 

    Wells, Jordann Ashley Logan Slovenne Denis (The University of Edinburgh, 2018-07-09)
    The work described in this thesis concerns the synthesis of actinide complexes and their reactivity towards small unsaturated molecules. Complexes bearing tetraphenoxide, borohydride and boroxide ligands have been ...
  • High-resolution Fourier transform ion cyclotron resonance mass spectrometry and nuclear magnetic resonance spectroscopy of humic substances 

    Blackburn, John William Teasdale (The University of Edinburgh, 2018-07-09)
    Humic substances (HS) are described as a complex mixture of organic molecules formed by incomplete decomposition of plant, animal and microbial matter. They are found in soil, water and air and have many environmental ...
  • Development of Halomethyl-Triazole reagents for installation of protein post-translational modification mimics 

    Brewster, Richard Christian (The University of Edinburgh, 2018-07-09)
    Triazoles have been widely used as amide bond isosteres in chemical biology as linkers and to enhance proteolytic stability. The use of triazoles has grown exponentially since the discovery of the copper (I) catalysed ...
  • Developing Earth-abundant metal-catalysts for hydrofunctionalisation 

    Paliga, James Francis (The University of Edinburgh, 2018-07-09)
    The iron-catalysed hydromagnesiation of styrene derivatives has been developed further from previous publications, expanding the electrophile scope to enable the regioselective formation of new carbon-carbon and ...
  • Exploiting anionically-tethered N-heterocyclic carbene complexes for small molecule activation 

    McMullon, Max William (The University of Edinburgh, 2018-07-09)
    N-heterocyclic carbenes (NHCs) can be used as ligands for organometallics complexes, which can then facilitate numerous catalytic applications, such as, C-H activation, small molecule activation and numerous materials ...
  • Developing dynamic combinatorial chemistry as a platform for drug discovery 

    Ekström, Alexander Gösta (The University of Edinburgh, 2018-07-09)
    Dynamic combinatorial chemistry (DCC) is a powerful tool to identify new ligands for biological targets. In the technique, library synthesis and hit identification are neatly combined into a single step. A labile ...
  • Designing reagents for the solvent extraction of critical metal resources 

    Doidge, Euan Douglas (The University of Edinburgh, 2018-07-09)
    The work in this thesis aims to develop new systems for the more efficient recovery of metals from aqueous solution using solvent extraction. Understanding the underlying coordination chemistry to improve hydrometallurgical ...
  • DNA-based logic 

    Bader, Antoine (The University of Edinburgh, 2018-07-09)
    DNA nanotechnology has been developed in order to construct nanostructures and nanomachines by virtue of the programmable self-assembly properties of DNA molecules. Although DNA nanotechnology initially focused on spatial ...
  • 2D and 3D applications of polymeric biomaterials 

    Venturato, Andrea (The University of Edinburgh, 2018-07-09)
    The field of biomaterials has seen huge development over the past decade with enormous efforts invested in discovering materials with improved biocompatibility, application and versatility. Polymers can display many ...
  • Biochemical and biophysical investigations into key malaria parasite proteins 

    Weir, Christopher Neil; Haggarty-Weir, Christopher Neil (The University of Edinburgh, 2018-07-09)
    Plasmodium falciparum, the most pestilential of the malaria parasite species, is responsible for ~450,000 direct deaths annually. Clinical disease is a consequence of the blood stage of the parasite’s lifecycle involving ...
  • Applications of tetrazines in chemical biology 

    Neumann, Kevin (The University of Edinburgh, 2018-07-09)
    The need for chemoselective bond formation within complex biological systems has driven much research in chemical biology and chemical medicine and has allowed control over the structure and biological properties of a ...
  • Advancements and understanding of Blister-Based Laser-Induced Forward-Transfer 

    Goodfriend, Nathan Thomas (The University of Edinburgh, 2018-07-09)
    Blister-Based Laser-Induced Forward-Transfer (BB LIFT) is a new method of particle transfer, capable of projecting complex and fragile particles into the gas phase. The technique uses a laser pulse to deform a metal or ...
  • Transition metal catalysis: a new paradigm in bioorthogonal drug activation 

    Clavadetscher, Jessica Veronica (The University of Edinburgh, 2017-11-30)
    Powerful tools have emerged in the past few years to allow the sensing, imaging and modulation of biological processes in living systems. Bioorthogonal organometallic reactions are transformations catalysed by transition ...
  • Total synthesis of phenolic natural products 

    De Silvestro, Irene (The University of Edinburgh, 2017-11-30)
    This thesis is regarded with the biomimetic total synthesis of phenolic natural products and describes two different projects. Chapter 1 introduces phenolic natural products, the most important biosynthetic pathways for ...
  • Use of acetylacetonate‐based paramagnetic metalloligands in the construction of supramolecular magnetic coordination capsules 

    O'Connor, Helen (The University of Edinburgh, 2018-07-09)
    In molecular magnetism, rational design and serendipity have played complementary roles in the synthesis of complexes which display a breadth of interesting physical characteristics. These range from the basic understanding ...
  • Tailoring the physical properties of energetic materials 

    Ward, Daniel W. (The University of Edinburgh, 2017-11-30)
    Energetic materials are a class of material that have large amounts of chemical energy stored within their molecular structure. This energy is released upon decomposition, generally in the form of rapidly expanding, hot ...
  • Evolution of restriction-modification systems 

    Bower, Edward Kenneth Merrick (The University of Edinburgh, 2017-07-07)
    Restriction Modification (R-M) systems prevent the invasion of foreign genetic material into bacterial cells and are therefore important in maintaining the integrity of the host genome. The spread of antibiotic resistance, ...
  • Effect of guest uptake and high pressure on Zn- and Zr- metal-organic frameworks 

    Hobday, Claire Louise (The University of Edinburgh, 2017-07-07)
    Porous materials are essential to our everyday lives, for example as an effective catalyst in the cracking of crude oil, or as water softeners in washing powder. When developing novel functional porous materials, it is ...

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