An investigation of the in vitro liphydroxylation of DOC was undertaken. The chief aim
of this work being the attempted elucidation of the
role of cofactors like fumarate in the liphydroxylation reaction. Advantage has been taken of
a specific, sensitive, and accurate method for the
determination of progesterone and related steroids
in tissue preparations, which has been developed in
this Department (Taylor, 1951).