OBJECTIVES: The main aim of this research was to investigate factors which predict
Health-Related Quality of Life (HRQOL) in adolescents with Inflammatory Bowel
Disease (IBD). A secondary aim was to investigate agreement between parent
reported and adolescent reported HRQOL. A further aim was to investigate gender
differences in reported HRQOL.
METHOD: Fifty-seven adolescents with IBD attending a Gastroenterology
outpatients' clinic completed measures of anxiety (Spence Children's Anxiety
Scale), depression (Beck Depression Inventory), self esteem (Rosenberg Self Esteem
Scale), parental overprotection (Parental Bonding Instrument) and HRQOL
(Pediatric Quality of Life Inventory -PedQL). Parents completed measures of
anxiety (Beck Anxiety Inventory), depression (Beck Depression Inventory) and the
parent version of the PedsQL.
RESULTS: Adolescent and parental psycho-social functioning and maternal
overprotection were found to be significantly associated with HRQOL outcomes.
Regression analysis indicated that gender, individual psychological functioning and
parental functioning as a whole predicted HRQOL outcomes. Agreement on parent
and self reported HRQOL was moderate to good across all domains. Females
reported poorer HRQOL than males on domains of physical, social and psycho¬
CONCLUSIONS: This study highlights the influence of individual and parental factors
on the quality of life of adolescents with IBD. Clinical and theoretical implications
of these findings are discussed.