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dc.contributor.authorAddison, Patricken
dc.date.accessioned2018-01-31T11:42:28Z
dc.date.available2018-01-31T11:42:28Z
dc.date.issued2006en
dc.identifier.urihttp://hdl.handle.net/1842/27899
dc.description.abstracten
dc.description.abstractHYPOTHESIS: That skeletal muscle, throughout the body, can be preconditioned to better withstand prolonged periods of ischaemia, by first subjecting a remote muscle to brief, non-invasive and sub-lethal, cycles of ischaemia and reperfusion, using a hindlimb tourniquet.en
dc.description.abstractAIMS: The aims of the project were:en
dc.description.abstract1) To test the hypothesis, using porcine Latissimus Dorsi, Rectus Abdominis and Gracilis muscle flaps.en
dc.description.abstract2) To define the potency and time course of the protective effect of remote ischaemic preconditioning in this model.en
dc.description.abstract3) To assess the physiological effects of remote ischaemic preconditioning both in terms of energy metabolism during subsequent prolonged ischaemia, and postischaemic blood flowen
dc.description.abstract4) To investigate the mechanism of remote ischaemic preconditioning in this model.en
dc.publisherThe University of Edinburghen
dc.relation.isreferencedbyAlready catalogueden
dc.subjectAnnexe Thesis Digitisation Project 2017 Block 16en
dc.titleRemote, non-invasive ischaemic preconditioning of skeletal muscle flaps against ischaemic necrosis : efficacy and mechanismen
dc.typeThesis or Dissertationen
dc.type.qualificationlevelen
dc.type.qualificationnameMD Doctor of Medicineen


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