The form and structure of the human claustrum
Rae, Alistair S.L.
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The sheet of grey matter lying between the insular cortex and putamen is said to have been first described (as the nucleus taeniaformis) by Vicq d'Azyr. The name "claustrum" was introduced by Burdach.The claustrum was early assumed to constitute the deepest layer of the insular cortex. This view was accepted by many authors and is still quoted in some current text -books. The inadequacy of the evidence upon which it was based has been demonstrated by several anatomists, especially by Professor Ebers Landau of Lausanne, who devoted an important series of papers to the matter. It is therefore necessary to investigate the claustrum as a formation sui generi s . The facts at present available suggest that the claustrum is no mere dependancy or stratum of the insular cortex, and that it is connected to many regions of the brain. Its function is quite unknown.Relatively little study has been given to the claustrum itself; many relevant facts are scattered in publications primarily concerned with other matters; ontogenetic and phylogenetic researches have, so far, tended to confuse rather than to clarify the subject.The present work is restricted to the investigation of the macroscopic form and histological characteristics of the adult human claustrum, to a discussion of the literature dealing with these topics, and to an attempt to synthetize the information thus obtained.