1. Fourteen cases exhibiting signs of peripheral
nerve degeneration, have been studied; five cases
treated by Dr Ritchie Russell have also been included.
. A deficiency of vitamin B₁ of varying degree was
found to be concerned: - (a) By dietary deficiency;
(b) by gastro- intestinal derangement conditioning a state of deficiency;
(c) by response to specific treatment by
parenterally administered vitamin B₁.
3. Achlorhydria was found to be an important
aetiological factor in fourteen cases.
4. The most rapid response to treatment was obtained
by parenteral injection of the vitamin; 1000
international units for three consecutive days
followed by 500 international units per day, gave
eminently satisfactory results.
5. As other dietary deficiencies are frequently concerned in the clinical phenomena ôf these cases,
a diet adequate in all respects was prescribed.