Stenotrophomonas maltophilia in patients with bronchiectasis
Perez Fernandez, Elena
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Bronchiectasis is an acquired irreversible bronchopulmonary disease where bronchial walls in the lungs are permanently inflamed and dilated. This leads to a ‘vicious cycle’ between chronic bacterial infection and immune dysregulation. One of the bacterial infections patients with bronchiectasis experience is S. maltophilia, a Gram-negative gamma proteobacteria with intrinsic multidrug resistance and widely found in the environment. S. maltophilia is also a common infection in CF patients but has poorly been characterised in bronchiectasis. This study looks at its significance in bronchiectasis and tries to establish a comparison between environmental and clinical strains as well as to elucidate the question of its pathogenicity which is still controversial.