Experimental middle cerebral artery occlusion: a study of the effects of controlled hypotension on infarct size, cerebral oedema, and cerebral blood flow in a rat model of focal cerebral ischaemia, and a preliminary evaluation of the effects of immunosuppression by irradiation on the development of cerebral oedema
Strachan, Roger D.
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Declerck, Marlies Hilde Philip (The University of Edinburgh, 2014-07-04)Cerebral palsy is the most common motor disability in childhood. The disorders of movement and posture are characterised by abnormal patterns of movement related to defective movement coordination and regulation of muscle ...
Characterisation of a mouse model of chronic cerebral hypoperfusion and its application to investigating the impact of hypoperfusion on the development of Alzheimer’s disease Coltman, Robin Bruce (The University of Edinburgh, 2012-06-22)The integrity of brain white matter is vital for the interneuronal signalling between distinct brain regions required for normal cognitive function. White matter integrity is compromised with ageing and could contribute ...
Impact of normal ageing and cerebral hypoperfusion on myelinated axons and its relation to the development of Alzheimer’s disease Karali, Kanelina (The University of Edinburgh, 2014-06-28)Cerebral hypoperfusion can occur in normal ageing and is proposed to underlie white matter disturbances observed in the ageing brain. Moreover, cerebral hypoperfusion and white matter attenuation are early events in the ...