Experimental middle cerebral artery occlusion: a study of the effects of controlled hypotension on infarct size, cerebral oedema, and cerebral blood flow in a rat model of focal cerebral ischaemia, and a preliminary evaluation of the effects of immunosuppression by irradiation on the development of cerebral oedema
Strachan, Roger D.
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Rannikmäe, Kristiina (The University of Edinburgh, 2017-07-08)Background: Cerebral small vessel disease (SVD) causes substantial cognitive, psychiatric and physical disabilities. Despite its common nature, SVD pathogenesis and molecular mechanisms remain poorly understood, and ...
Investigating the risk of intracranial haemorrhage or focal neurological deficit in adults diagnosed with cerebral cavernous malformation Horne, Margaret Anne (The University of Edinburgh, 2015-07-04)Background A cerebral cavernous malformation (CCM) is a small cluster of thin-walled, dilated blood vessels within the brain which is prone to bleed. Although the quantity of blood leaking tends to be small, even a small ...
Antithrombotic drug use, cerebral microbleeds and intracerebral haemorrhage: a systematic review of published and unpublished studies Lovelock, CE; Cordonnier, C; Naka, H; Al-Shahi Salman, R; Sudlow, Cathie; Sorimachi, T; Werring, DJ; Gregoire, SM; Imaizumi, T; Lee, SH; Briley, D; Jackson, Caroline Anne; Dennis, M; Wardlaw, Joanna M; Potter, Gillian Margaret; Rothwell, PM (American Heart Association, 2010-06)Background and Purpose— Cerebral microbleeds (MB) are potential risk factors for intracerebral hemorrhage (ICH), but it is unclear if they are a contraindication to using antithrombotic drugs. Insights could be gained by ...