Experimental middle cerebral artery occlusion: a study of the effects of controlled hypotension on infarct size, cerebral oedema, and cerebral blood flow in a rat model of focal cerebral ischaemia, and a preliminary evaluation of the effects of immunosuppression by irradiation on the development of cerebral oedema
Strachan, Roger D.
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Shi, Yulu (The University of Edinburgh, 2018-06-30)Cerebral small vessel disease (SVD) is associated with increased risks of stroke and dementia, however the mechanisms remain unclear. Low cerebral blood flow (CBF) has long been suggested and accepted, but clinical ...
Rannikmäe, Kristiina (The University of Edinburgh, 2017-07-08)Background: Cerebral small vessel disease (SVD) causes substantial cognitive, psychiatric and physical disabilities. Despite its common nature, SVD pathogenesis and molecular mechanisms remain poorly understood, and ...
Investigating the risk of intracranial haemorrhage or focal neurological deficit in adults diagnosed with cerebral cavernous malformation Horne, Margaret Anne (The University of Edinburgh, 2015-07-04)Background A cerebral cavernous malformation (CCM) is a small cluster of thin-walled, dilated blood vessels within the brain which is prone to bleed. Although the quantity of blood leaking tends to be small, even a small ...