Edinburgh Medical School is one of two schools at the College of Medicine and Veterinary Medicine at the University of Edinburgh. The Edinburgh Medical School integrates research and teaching across our three Deaneries: Biomedical Sciences, Clinical Sciences and Molecular,Genetic and Population Health Sciences.

Recent Submissions

  • Studies on the procurement of blood coagulation factor VIII 

    Farrugia, Albert (The University of Edinburgh, 1984)
    Coagulation factor VIII is needed for the treatment of patients with haemophilia. Requirements for factor VIII are important in determining the numbers of blood donations to be collected in Scotland. The final yield ...
  • Role of the Wilms’ tumour-1 (WT1) gene in adult angiogenesis 

    McGregor, Richard James (The University of Edinburgh, 2015-11-27)
    In 1899, the German surgeon Max Wilms hypothesised that different cell types in a variety of childhood kidney cancers were all derived from the mesodermal layer during embryonic development. Nearly a century later, the ...
  • Acanthamoeba and the bacterial pathogen interactions 

    Asif, Muhammad (The University of Edinburgh, 2015-11-27)
    The present study investigates Acanthamoeba-bacteria interaction and how this relation can influence human health aiming at the influence of bacteria on Acanthamoeba in terms of their isolation and diversity, and the ...
  • Modelling the prevalence, healthcare costs and number of deaths in chronic obstructive pulmonary disease in England and Scotland 

    McLean, Susannah Caroline (The University of Edinburgh, 2015-11-27)
    Introduction Chronic obstructive pulmonary disease (COPD) has emerged as a major policy focus for health systems throughout Western Europe. This reflects the increased prevalence, associated healthcare utilisation and ...
  • Genetic and environmental determinants of Paget's disease of bone. 

    Rios Visconti, Micaela (The University of Edinburgh, 2015-11-27)
    Genetic factors play an important role in the pathogenesis of Paget’s Disease of Bone (PDB). The most important predisposing gene is SQSTM1 which is mutated in about 10% of patients, additionally common variants at seven ...
  • Role of heat shock protein 90 in modulating ischemia-reperfusion injury in the kidney 

    O'Neill, Stephen (The University of Edinburgh, 2015-11-27)
    Kidney transplantation is the gold standard treatment for end-stage renal disease. Renal ischemia-reperfusion injury is an unavoidable consequence of the transplantation procedure and is responsible for delayed graft ...
  • Critical review: evolution and impact of ultrasound guidance on brachial plexus anaesthesia. 

    McCartney, Colin John Lindsay (The University of Edinburgh, 2015-11-27)
    Brachial plexus block (BPB) techniques provide significant benefits including better pain control, faster discharge and reduced adverse effects compared to general anaesthesia. Prior to 2005 BPBs were performed using ...
  • Changes in blood in disease 

    Lückhoff, James (The University of Edinburgh, 1902)
  • Osteoprotegerin antibodies in the pathogenesis of osteoporosis 

    Riches, Philip Leonard (The University of Edinburgh, 2015-11-27)
    Osteoporosis is a common complication of many autoimmune diseases that is typically attributed to disease specific factors rather than a direct autoimmune process. This thesis arises from the investigation of a patient ...
  • Modelling Brugada Syndrome using induced pluripotent stem cells 

    Sendfeld, Franziska (The University of Edinburgh, 2015-11-27)
    Objective: Brugada Syndrome is an autosomal dominant congenital heart disease that is responsible for 20% of sudden deaths of patients with structurally normal hearts. The majority of mutations involve the cardiac sodium ...
  • Cell therapy for chronic liver disease 

    Thomas, James A. (The University of Edinburgh, 2015-11-27)
    There is a growing literature of clinical studies of bone marrow (BM) cell therapy for liver cirrhosis. At present, the optimum choice of cell type(s) and the mechanism(s) of effect remain undefined. Cells of the ...
  • Detecting selection in the evolution of cancer genomes 

    Pethick, Joanna Margaret (The University of Edinburgh, 2015-11-27)
    Cancer is a disease of the genome, requiring mutation or epimutation of specific genes to develop. The subsequent progression of cancer and response to therapies is also dictated to some degree by new mutation and clonal ...
  • Investigation of the impact of HNPCC gene deficiency on outcome in epithelial ovarian cancer 

    Xiao, Xue (The University of Edinburgh, 2015-11-27)
    Hereditary non-polyposis colon cancer syndrome (HNPCC) is associated with an increased risk of developing several types of cancer and is the most common cause of hereditary ovarian cancer after BRCA1 and BRCA2 mutations. ...
  • Morphological properties of articular chondrocytes in various experimental and clinical conditions 

    Karim, Asima (The University of Edinburgh, 2015-11-27)
    Previous work has suggested that there exists a relationship between chondrocyte morphology and matrix metabolism. Changes to chondrocyte morphology have been reported in human cartilage however it is unclear if these ...
  • Social and emotional processing in borderline personality disorder 

    Nicol, Katie (The University of Edinburgh, 2015-11-27)
    Objective Borderline Personality Disorder (BPD) is a common and serious mental illness, associated with severe emotional dysregulation, a high risk of suicide and self-harm. Those with a diagnosis of BPD often display ...
  • Multisensory integration of spatial cues in old age. 

    Bates, Sarah Louise (The University of Edinburgh, 2015-11-27)
    Spatial navigation is essential for everyday function. It is successfully achieved by combining internally generated information – such vestibular and self-motion cues (known as path integration) – with external sources ...
  • Effects of hippocampal lesions on acquisition and memory for context 

    Beange, Iona Margaret (The University of Edinburgh, 2008-12-05)
    Hippocampal lesions impair memory for context in some tasks but not others. Factors that may contribute include: a) whether context is encoded in configurally or elementally; b) whether lesions are performed before or ...
  • Discovery of novel prognostic tools to stratify high risk stage II colorectal cancer patients utilising digital pathology 

    Caie, Peter David (The University of Edinburgh, 2015-11-27)
    Colorectal cancer (CRC) patients are stratified by the Tumour, Node and Metastasis (TNM) staging system for clinical decision making. Additional genomic markers have a limited utility in some cases where precise targeted ...
  • Effects of glucocorticoids in macrophages 

    Jubb, Alasdair (The University of Edinburgh, 2015-11-27)
    Glucocorticoids (GC) are powerful metabolic hormones with anti-inflammatory actions. Despite major side effects they remain widely prescribed therapies. GC regulates gene expression through an intracellular receptor (GR), ...
  • Alcohol related cancers in Scotland 

    Grant, Ian (The University of Edinburgh, 2015-07-04)
    Introduction: There is considerable epidemiologic evidence that drinking alcoholic beverages is associated with an increased risk for certain cancers (i.e. cancers of the upper-aero digestive tract) though the evidence ...

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