Now showing items 1-4 of 4
A learning deficit related to age and b-amyloid plaques in a mouse model of Alzheimer's disease
(Nature Publishing Group, 2000-12-21)
Mice that overexpress the human mutant amyloid precursor protein (hAPP) show learning deficits, but the apparent lack of a relationship between these deficits and the progressive b-amyloid plaque formation that the hAPP ...
Reversible neural inactivation reveals hippocampal particin several memory processesipation
(Nature Publishing Group, 1999-10)
Studies of patients and animals with brain lesions have implicated the hippocampal formation in spatial, declarative/relational and episodic types of memory. These and other types of memory consist of a series of ...
Glutamate-receptor-mediated encoding and retrieval of paired-associate learning
(Nature Publishing Group, 2003-07-10)
Paired-associate learning is often used to examine episodic memory in humans (1). Animal models include the recall of foodcache locations by scrub jays (2) and sequential memory (3,4). Here we report a model in which ...
Flies put the buzz back into long-term-potentiation
(Nature Publishing Group, 2002-04)
Two new papers show that an atypical protein kinase C may mediate the maintenance of long-term potentiation in the mouse hippocampus and of associative memory in Drosophila.