Edinburgh Research Archive

• Design and development of novel mTOR and SRC family kinase inhibitors via a phenotypic drug discovery approach 

  Fraser, Craig (The University of Edinburgh, 2015-11-27)

  Traditionally, drug discovery programs have focused on prioritising compounds by their affinity to a specific target in isolation, which was hypothesised to be the cause of a particular disease. Through chemical inhibition, ...

• Manipulating macrophages to enhance liver regeneration 

  Stutchfield, Benjamin Mark (The University of Edinburgh, 2015-07-04)

  Acute liver failure confers a high risk of death, with liver transplantation offering the only effective therapy for life-threatening cases. Hepatic macrophages are crucial for innate immune integrity and effective ...

• Epidemiology of stroke and its subtypes in Chinese populations 

  Tsai, Chung-Fen (The University of Edinburgh, 2015-07-04)

  Background: Chinese populations have been reported to have a higher stroke incidence as well as different stroke epidemiology compared with white populations. However, reliable comparisons have been precluded by a lack ...

• Multisystem functional characterisation of motile ciliopathy genes HEATR2 and ZMYND10 

  Mali, Girish Ram (The University of Edinburgh, 2015-11-27)

  Cilia are polarized extensions of the cells microtubule-based cytoskeleton dedicated to sensory, signaling and motility-related functions. In mammals, there are two main types of cilia, immotile and motile, where motile ...

• Improved predictive models for pre-clinical drug toxicity studies 

  Navarro, Maria Dolores; Navarro-Zornoza, Maria Dolores (The University of Edinburgh, 2015-07-04)

  Increasingly, drug-induced liver injury is one of the main reason for drugs to be withdrawn from the market even after passing toxicity studies in pre-clinical and clinical trials because of risks of toxicity and ineffective ...

• Effects of pituitary extract and chloroform upon the blood-vessels 

  Campbell, J. Argyll (The University of Edinburgh, 1914)

• Development of the retina in amphibia : an embryological and cytological study 

  Cameron, John (The University of Edinburgh, 1904)

• Alterations in the apoptotic: mitotic ratio: an early indicator of breast cancer sensitivity to tamoxifen? 

  Cameron, David (The University of Edinburgh, 1997)

• Frequency, incidence and duration of various complications met with in a series of 500 consecutive cases of scarlet fever 

  Cairns, James William (The University of Edinburgh, 1914)

• Notes on twelve cases treated in the University Surgical Wards of the Royal Infirmary, Edinburgh 

  Caird, Andrew J. (The University of Edinburgh, 1914)

• Progressive muscular dystrophies: illustrated by two cases 

  Caine, Nathaniel (The University of Edinburgh, 1899)

• Intra-cranial tumors with special reference to the pituary body 

  Cadman, Ernest Stanley Radford (The University of Edinburgh, 1896)

• Studies in reperfusion injury and its role in the immediate graft function following liver transplantation 

  Bzeizi, Khalid I. (The University of Edinburgh, 1998)

• Histology of lymphatic glands 

  Bunting, Thomas Lowe (The University of Edinburgh, 1904)

• Phenomenological correlates of acting on delusions 

  Buchanan, Alec (The University of Edinburgh, 1996)

• Blood and protein loss in whole gut lavage fluid in gastrointestinal disease 

  Brydon, W. Gordon (The University of Edinburgh, 1996)

• Still birth and neo natal death: observations on their causes, pathology and prevention: based upon a detailed investigation into 400 cases occurring in the Edinburgh Royal Maternity Hospital 

  Browne, Francis.J. (The University of Edinburgh, 1925)

• Investigation of the effects of hyaluronan on human monocytes and macrophages in inflammatory processes 

  Bruce, Lorna Jacqueline (The University of Edinburgh, 1999)

• Purification and cDNA cloning of human placental 11B-hydroxysteroid dehydrogenase 

  Brown, Roger W. (The University of Edinburgh, 1996)

• Molecular interactions between DNA gyrase and the quinolone antibacterials 

  Brown, Janice C. (The University of Edinburgh, 1997)

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