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Please use this identifier to cite or link to this item:
http://hdl.handle.net/1842/687
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| Title: | Asymmetric leaves1 mediates leaf patterning and stem cell function in Arabidopsis |
| Authors: | Byrne, Mary E
Barley, Ross
Curtis, Mark
Arroyo, Juana Maria
Dunham, Maitreya
Hudson, Andrew
Martienssen, Robert A |
| Issue Date: | 21-Dec-2000 |
| Citation: | Byrne ME, Barley R, Curtis M, Arroyo JM, Dunham M, Hudson A, Martienssen RA, NATURE, 408 (6815): 967-971 DEC 21 2000 |
| Publisher: | Nature Publishing Group |
| Abstract: | Meristem function in plants requires both the maintenance of
stem cells and the specification of founder cells from which lateral
organs arise. Lateral organs are patterned along proximodistal,
dorsoventral and mediolateral axes (1,2). Here we show that the
Arabidopsis mutant asymmetric leaves1 (as1) disrupts this process.
AS1 encodes a myb domain protein, closely related to
PHANTASTICA in Antirrhinum and ROUGH SHEATH2 in
maize, both of which negatively regulate knotted-class homeobox
genes. AS1 negatively regulates the homeobox genes KNAT1 and
KNAT2 and is, in turn, negatively regulated by the meristematic
homeobox gene SHOOT MERISTEMLESS. This genetic pathway
defines a mechanism for differentiating between stem cells and
organ founder cells within the shoot apical meristem and demonstrates
that genes expressed in organ primordia interact with
meristematic genes to regulate shoot morphogenesis |
| Keywords: | Asymmetric
leaves
mediates
leaf
patterning
stem cell
function
Arabidopsis |
| URI: | www.nature.com
http://hdl.handle.net/1842/687 |
| Appears in Collections: | Biological Sciences publications
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